Can autoimmune disease go into remission?

Yes, autoimmune disease can go into remission. Remission means your symptoms are significantly reduced or absent, though it doesn't always mean the disease is cured. Many people with lupus, rheumatoid arthritis, Hashimoto's, and other autoimmune conditions achieve remission through a combination of medical treatment, lifestyle changes, stress management, and anti-inflammatory nutrition. At Invigorate, we focus on realistic small steps toward remission that work even on flare days.

What is the P.A.R. method for autoimmune disease?

P.A.R. stands for Process, Adapt, and Reclaim — Invigorate's framework for living well with autoimmune disease. Process means finding your footing after diagnosis. Adapt means building routines that work with your body, including flare management strategies. Reclaim means living a meaningful, purposeful life even with an autoimmune condition. This approach was developed by Karin Wagner, a lupus warrior and health coach.

What autoimmune conditions does Invigorate support?

Invigorate supports people with 20+ autoimmune conditions including lupus (SLE), rheumatoid arthritis (RA), Hashimoto's thyroiditis, Graves' disease, multiple sclerosis (MS), psoriatic arthritis, Sjogren's syndrome, inflammatory bowel disease (Crohn's and ulcerative colitis), and many more. The coaching and podcast address the shared experiences across different autoimmune diagnoses.

How do you manage autoimmune disease flares?

Managing autoimmune flares involves several strategies: rest and pacing (avoiding overexertion), anti-inflammatory diet adjustments, stress reduction techniques like breathwork and mindfulness, staying connected with your rheumatologist or specialist, and maintaining realistic routines that can flex on hard days. Invigorate's coaching teaches people to reset without shame or guilt when flares disrupt their plans.

What is the Invisible Strength podcast about?

The Invisible Strength Podcast shares real stories from autoimmune warriors — people living with lupus, RA, Hashimoto's, chronic pain, and other chronic conditions. Hosted by Karin Wagner and Chris Burton, each episode covers the emotional weight of diagnosis, real-life strategies for managing symptoms, and stories of people who have reclaimed their energy and quality of life. The podcast has 75+ episodes, is in Season 3, and is always free.

Is autoimmune disease coaching effective?

Autoimmune disease coaching can be highly effective as a complement to medical treatment. Coaching helps people develop personalized strategies for energy management, flare recovery, emotional resilience, and lifestyle adjustments. Invigorate's coaching program has helped 1,000+ people with autoimmune conditions across 20+ diagnoses develop sustainable routines that support their overall wellbeing and quality of life.

Episode 77 · Invisible Strength Podcast

Chasing Goals, Not Ghosts: Mireille Siné on Running 200 Miles with Lupus

June 10, 2026 · Hosts: Karin Wagner & Chris Burton

▶ Listen on Spotify

About This Episode

Lupus put Mireille Siné in the ICU in college. She came back to run 14 marathons, 5 ultras, and 200 miles from Boston to New York City — becoming the first Black woman to complete that run.

In this episode, Karin and Chris talk with Mireille — certified run coach, AIP nutrition coach, and unstoppable autoimmune warrior. Mireille shares her full story: the college stress that preceded her lupus diagnosis, the blood clot that took three ER visits to catch, chemotherapy and medical leave, and the slow, deliberate comeback that started with a quarter-mile run.

They get practical too: how Mireille structures training around flares with her stoplight protocol, why sleep is her non-negotiable recovery anchor, how she approaches nutrition for inflammation, and how to tell normal training fatigue from the start of a flare. Plus the mental game — and what it means to chase goals instead of ghosts.

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About Mireille Siné

Mireille Siné is a certified run coach and AIP nutrition coach living with lupus. After being hospitalized in college with a blood clot and undergoing chemotherapy, she rebuilt her life through running — going on to complete 14 marathons, 5 ultramarathons, and a historic 200-mile run from Boston to New York City as the first Black woman to do so. She now coaches other autoimmune athletes using her proven stoplight training protocol.

Find Mireille: @heycoachmireille · coachedbymireille.com

Key Takeaways

“You’re not gonna get anywhere chasing a ghost.” Stop comparing your current capacity to who you were before diagnosis — focus on who you’re becoming.

The stoplight protocol: Green means go at full effort, yellow means modify, red means rest. Knowing which light you’re at changes everything about training with autoimmune disease.

Sleep is non-negotiable. For Mireille, sleep is the single biggest recovery lever — more important than any supplement or training tweak.

The first comeback step was a quarter-mile run. You don’t need to start big. You just need to start.

Community is medicine. Surrounding yourself with people who get it — who see your invisible struggle — changes your relationship with your diagnosis.

Episode Chapters

00:02 — Meet Mireille
02:02 — Training with compassion
04:08 — The lupus diagnosis story
09:14 — Coming back: the first mile
13:04 — Self-doubt and setbacks
16:01 — The marathon that means the most
22:01 — Sleep, nutrition, community
26:54 — Coaching autoimmune athletes
30:23 — The stoplight protocol for flares
34:14 — Fatigue vs. flare: how to tell
35:39 — “Chasing a ghost” — the mindset shift
40:44 — What invisible strength means
42:25 — What’s next for Mireille

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EP. 77: Chasing Goals, Not Ghosts — Mireille Siné on Running 200 Miles with Lupus